Saturday, September 24, 2011

Penn State Scientists Discover AAV2 Virus That Kills Breast Cancer Cells in Laboratory

The discovery of a naturally occurring virus that can kill breast cancer cells is a promising and amazing development from the scientists at Penn State. It could potentially save thousands of lives. The results were lab-based, so hopefully, these results will translate as favorably to clinical trials and other studies using this advancement in the future.

A nondisease-causing virus kills human breast cancer cells in the laboratory, creating opportunities for potential new cancer therapies, according to Penn State College of Medicine researchers who tested the virus on three different breast cancer types that represent the multiple stages of breast cancer development.

Adeno-associated virus type 2 (AAV2) is a virus that regularly infects humans but causes no disease...Researchers used an unaltered, naturally occurring version of AAV2 on human breast cancer cells...

...In tissue culture dishes in the laboratory, 100 percent of the cancer cells are destroyed by the virus within seven days, with the majority of the cell death proteins activated on the fifth day. In another study, a fourth breast cancer derived cell line, which is the most aggressive, required three weeks to undergo cell death.

Source: Penn State University

Image Source: barcoder96 (licensed per Creative Commons Attribution-Share Alike 2.0 Generic license)

Tuesday, September 20, 2011

Flu Vaccine Ingredients & Package Inserts for FDA-Approved Vaccines in USA (2011-2012)

Image: David Dees

**UPDATE (September 23, 2012)** - For a list of the ingredients in the approved 2012-2013 flu vaccines, please see my blog post entitled REMIXX WORLD!: Flu Vaccine Ingredients & Package Inserts for FDA-Approved Vaccines in the United States of America (2012-2013)


I recently posted a photo in another blog post and briefly discussed the 2011 flu vaccine. Suddenly, I was getting Google hits, so I guess people are still interested in the flu vaccine ingredients. I thought I beat that horse to death back in 2009-10, but I guess not. Therefore, below are five (5) flu vaccines approved for use in the United States of America.

Please note that this 2011 flu vaccine will contain a vaccine for the H1N1 "swine flu" as well. You can read my 2009 and 2010 analysis on the H1N1 vaccine by clicking here.


1. FLUZONE® by Sanofi Pasteur (FDA link)

Here is the package insert information from one such 2011 flu vaccine called Fluzone® by Sanofi Pasteur.

Depending on the specific vaccine that you may get, Fluzone can potentially include any of the following ingredients:

  • Formaldehyde
  • Gelatin
  • Octylphenol Ethoxylate - an emulsifier
  • Thimerosal (a mercury derivative) (in the 0.5 mL multi-dose)
For a table of the ingredients, click here and here.

2. FLUVIRIN® by Novartis (FDA link)

For the official package insert for this vaccine, here it is courtesy of Novartis. The ingredients are listed on in Section 11 on page 20, but I will quote it here for you. Please note that multidose of the vaccine may also contain betapropiolactone and according the CDC website, betapropiolactone is a potential carcinogen. The multidose also contains nonylphenol ethoxylate which is used in detergents.

FLUVIRIN® is a trivalent, sub-unit (purified surface antigen) influenza virus vaccine prepared from virus propagated in the allantoic cavity of embryonated hens’ eggs inoculated with a specific type of influenza virus suspension containing neomycin and polymyxin. Each of the influenza virus strains is harvested and clarified separately by centrifugation and filtration prior to inactivation with betapropiolactone. The inactivated virus is concentrated and purified by zonal centrifugation. The surface antigens, hemagglutinin and neuraminidase, are obtained from the influenza virus particle by further centrifugation in the presence of nonylphenol ethoxylate, a process which removes most of the internal proteins. The nonylphenol ethoxylate is removed from the surface antigen preparation.FLUVIRIN® is a homogenized, sterile, slightly opalescent suspension in a phosphate buffered saline. FLUVIRIN® has been standardized according to USPHS requirements for the 2010-2011 influenza season and is formulated to contain 45 mcg hemagglutinin (HA) per 0.5-mL dose in the recommended ratio of 15 mcg HA of each of the following 3 viruses: A/California/7/2009, NYMC X-181 (H1N1); A/Victoria/210/2009, NYMC X-187 (H3N2) (an A/Perth/16/2009-like virus); and B/Brisbane/60/2008.The 0.5-mL prefilled syringe presentation is formulated without preservative. However, thimerosal, a mercury derivative used during manufacturing, is removed by subsequent purification steps to a trace amount (≤ 1 mcg mercury per 0.5-mL dose).The 5-mL multidose vial formulation contains thimerosal, a mercury derivative, added as a preservative. Each 0.5-mL dose from the multidose vial contains 25 mcg mercury.Each dose from the multidose vial or from the prefilled syringe may also contain residual amounts of egg proteins (≤ 1 mcg ovalbumin), polymyxin (≤ 3.75 mcg), neomycin (≤ 2.5 mcg), betapropiolactone (not more than 0.5 mcg) and nonylphenol ethoxylate (not more than 0.015% w/v).
The tip caps of the FLUVIRIN® prefilled syringes may contain natural rubber latex. The multidose vial stopper and the syringe stopper/plunger do not contain latex.

3. FluMist by MedImmune, LLC (FDA link)

As always with the intranasal vaccines, this one has live viruses, including H1N1 and H3N2! Please make note of that information if/when you select a particular vaccine (or not). You can find the specific ingredients on page 3 in section 11, but the ones to notes are MSG and porcine gelatin (processed pigskins).

Each pre-filled refrigerated FluMist sprayer contains a single 0.2 mL dose. Each 0.2 mL dose contains 106.5-7.5 FFU of live attenuated influenza virus reassortants of each of the three strains: A/California/7/2009 (H1N1), A/Perth/16/2009 (H3N2), and B/Brisbane/60/2008. Each 0.2 mL dose also contains 0.188 mg/dose monosodium glutamate, 2.00 mg/dose hydrolyzed porcine gelatin, 2.42 mg/dose arginine, 13.68mg/dose sucrose, 2.26mg/dose dibasic potassiumphosphate, 0.96mg/dosemonobasic potassium phosphate, and 0.015 mcg/mL gentamicin sulfate. FluMist contains no preservatives.

4. FLULAVAL by GlaxoSmithKline (FDA link)

I've previously discussed FLULAVAL in the November 2009 blog posting FDA Approves GlaxoSmithKline's H1N1 "Swine Flu" FLULAVAL® Vaccine (Fifth Vaccine Maker in the USA). I don't know if it's the same ol' vaccine, different year, but let's find out. The ingredients are listed in Section 11, page 8. My major note is that this vaccine contains mercury!

FLULAVAL is a sterile, translucent to whitish opalescent suspension in a phosphate-buffered saline solution that may sediment slightly. The sediment resuspends upon shaking to form a homogeneous suspension. FLULAVAL has been standardized according to USPHS requirements for the 2011-2012 influenza season and is formulated to contain 45 mcg hemagglutinin (HA) per 0.5-mL dose in the recommended ratio of 15 mcg HA of each of the following 3 strains: A/California/7/2009 NYMC X-181 (H1N1), A/Victoria/210/2009 NYMC X-187 (H3N2) (an A/Perth/16/2009-like virus), and B/Brisbane/60/2008. Thimerosal, a mercury derivative, is added as a preservative. Each dose contains 25 mcg mercury. Each dose may also contain residual amounts of egg proteins (≤1 mcg ovalbumin), formaldehyde (≤25 mcg), and sodium deoxycholate (≤50 mcg). Antibiotics are not used in the manufacture of this vaccine.The vial stopper does not contain latex.

5. FLUARIX by GlaxoSmithKline (FDA link)

Interesting that this vaccine contains a few different ingredients than the other vaccines, particularly stuff like octoxynol-10 (an emulsifier) and polysorbate 80.

FLUARIX has been standardized according to USPHS requirements for the 2011-2012 influenza season and is formulated to contain 45 micrograms (mcg) hemagglutinin (HA) per 0.5-mL dose, in the recommended ratio of 15 mcg HA of each of the following 3 strains: A/California/7/2009 NYMC X-181 (H1N1), A/Victoria/210/2009 NYMC X-187 (H3N2) (an A/Perth/16/2009-like virus), and B/Brisbane/60/2008.FLUARIX is formulated without preservatives. FLUARIX does not contain thimerosal. Each 0.5-mL dose also contains octoxynol-10 (TRITON® X-100) ≤0.085 mg, α-tocopheryl hydrogen succinate ≤0.1 mg, and polysorbate 80 (Tween 80) ≤0.415 mg. Each dose may also contain residual amounts of hydrocortisone ≤0.0016 mcg, gentamicin sulfate ≤0.15 mcg, ovalbumin ≤0.05 mcg, formaldehyde ≤5 mcg, and sodium deoxycholate ≤50 mcg from the manufacturing process.

CVS Grim Reaper Promotes Flu Shot?

epic fail photos - Hinting At Something FAIL

The picture might be funny if there weren't toxic ingredients like formaldehyde in these flu vaccines. I haven't checked out the 2011 package inserts, but I did an intensive analysis on this blog for various flu vaccines in 2009 and 2010.

Here is the package insert information from one such 2011 flu vaccine called Fluzone® by Sanofi Pasteur.

Fluzone (Influenza Virus Vaccine) for intramuscular injection, Fluzone High-Dose (Influenza Virus Vaccine) for intramuscular injection, and Fluzone Intradermal (Influenza Virus Vaccine) for intradermal injection are inactivated influenza virus vaccines, prepared from influenza viruses propagated in embryonated chicken eggs. The virus-containing allantoic fluid is harvested and inactivated with formaldehyde.

Weather Modification Confirmed in the State of Texas

Science boosts South & West Texas rains:

Science boosts South & West Texas rains:

This one is for any reader who doesn't believe in weather modification. It is now confirmed in the State of Texas. You can check out the above videos, the embedded quote from a local Austin, Texas news station (KXAN), an official Texas State web page and/or previous articles that Remixx World! has posted about the subject. I wonder if the cloud seeding a/k/a weather modification in one part of the State had any effect on the record droughts that were suffered in other parts of Texas this summer.

The meteorologist who leads the state’s cloud seeding program says the technique is increasing annual rainfall in parts of West and South Texas.

“South of San Antonio, we had aircraft flying on a dozen days in the month of July treating what we deemed to be seedable storms,” said George Bomar, the manager of the Weather Modification Program for Texas Department of Licensing and Regulation Department.


Weather Modification - Currently, cloud-seeding projects designed to increase rainfall from convective cloud towers are conducted in nearly 31 million acres of Texas (or almost one-fifth of the state’s land area). In administering the Texas Weather Modification Act (enacted by the Texas Legislature in 1967), TDLR’s weather modification program issues licenses and permits for these projects, many of which have been in existence since 2000. The projects use specialized aircraft and sophisticated weather radar systems, operated by skilled meteorologists, at sites near Amarillo, Plains, Pecos, San Angelo, and Pleasanton. In addition, TDLR issues licenses and permits to other organizations, as well as individuals, responsible for carrying out weather modification operations for both rainfall enhancement and hail suppression. The aim of the regulatory function is to ensure that various methods of modifying the weather do not dissipate clouds nor inhibit their ability to produce rainfall to the detriment of people or property in the affected areas.

The program also sponsors and provides administrative and technical oversight for ongoing weather modification research and development activities. This includes the use of federal grants for exploratory, and confirmatory, cloud seeding experiments. TDLR issues reports on the results of cloud seeding research work and shares information on technological advances with other State agencies, governmental organizations, and interested individuals.

The TDLR staff also works with political subdivisions, other organizations, and individuals in the design, or modification, of rain enhancement projects as well as the implementation of new seeding strategies for augmenting rainfall over targeted watersheds.

Sunday, September 18, 2011

Quantum Physics 101 with Dr. Quantum's Double Slit Experiment (Animated Video)

I really should read up and educate myself more on quantum physics. My knowledge consists of the information discussed in the book Time Travel: A Guide for Beginners. However, this video piqued my interest, so I will be doing further research in the coming weeks and months. This video is a quick introduction to quantum physics and the double slit experiment. As one said about the behavior of electrons, before the electrons are observed, there are infinite possibilities, but when the electrons are observed, a possibility becomes reality.

Source: GodLikeProductions