Saturday, September 24, 2011

Penn State Scientists Discover AAV2 Virus That Kills Breast Cancer Cells in Laboratory

The discovery of a naturally occurring virus that can kill breast cancer cells is a promising and amazing development from the scientists at Penn State. It could potentially save thousands of lives. The results were lab-based, so hopefully, these results will translate as favorably to clinical trials and other studies using this advancement in the future.

A nondisease-causing virus kills human breast cancer cells in the laboratory, creating opportunities for potential new cancer therapies, according to Penn State College of Medicine researchers who tested the virus on three different breast cancer types that represent the multiple stages of breast cancer development.

Adeno-associated virus type 2 (AAV2) is a virus that regularly infects humans but causes no disease...Researchers used an unaltered, naturally occurring version of AAV2 on human breast cancer cells...

...In tissue culture dishes in the laboratory, 100 percent of the cancer cells are destroyed by the virus within seven days, with the majority of the cell death proteins activated on the fifth day. In another study, a fourth breast cancer derived cell line, which is the most aggressive, required three weeks to undergo cell death.

Source: Penn State University

Image Source: barcoder96 (licensed per Creative Commons Attribution-Share Alike 2.0 Generic license)

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